COMPUTATIONAL EVALUATION OF MARINE DEMOSPONGIAE SPONGES METABOLITES ACTIVITY AS MYCOLIC ACID BIOSYNTHESIS INHIBITORS IN MYCOBACTERIUM TUBERCULOSIS

Computational evaluation of marine demospongiae sponges metabolites activity as mycolic acid biosynthesis inhibitors in Mycobacterium tuberculosis

Background: Mycobacterium tuberculosis is a bacterium that has historically had a substantial impact on human health.Despite advances in understanding and management of tuberculosis (TB), the disease remains a crucial problem that necessitates ongoing work to discover effective drugs, minimize transmission, and improve global health outcomes.Method

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TikTok Tourette’s: Are We Witnessing a Rise in Functional Tic-Like Behavior Driven by Adolescent Social Media Use?

Jessica Frey,1 Kevin J Black,2 Irene A Malaty3 1Department of Neurology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA; 2Departments of Psychiatry, Neurology, Radiology, and Neuroscience, Washington University in St.Louis, St.Louis, MO, USA; 3Department of Neurology, Fixel Institute for Neurological Diseases, Uni

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Water-holding properties and electrochemical characterization of the soil under the Grand Deliverance Hall of the Chongshan Temple, Taiyuan City, China: providing the basis for preventing groundwater erosion in historic buildings

Abstract Many historic buildings are at serious risk of deterioration due to changes in the Lower Spray Arm Support moisture content of the soil under the buildings.Based on the typical deterioration problems of the Grand Deliverance Hall and the cultural relics in the hall, this study analyzes and concludes that the main factor affecting the gener

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